Publications
Determining the Efficacy, Feasibility, and Impact of Storage Conditions on At-Home Blood Collection Kits for Proteomic Studies
Postacute At-home blood collection kits have the potential to greatly increase the efficiency of blood collection for diagnostic or research purposes by reducing the cost and burden on participants, researchers, or physicians and eliminating the need for a phlebotomist, specialized equipment, and on-site processing. These kits have shown to be effective for studying specific blood metabolites and proteins, but for analyses targeting the entire proteome, their effectiveness is unknown.
Determining the incidence, risk factors and biological drivers of irritable bowel syndrome (IBS) as part of the constellation of postacute sequelae of SARS-CoV-2 infection (PASC) outcomes in the Arizona CoVHORT-GI: a longitudinal cohort study
Postacute sequelae of SARS-CoV-2 infection (PASC) are extensive. Also known as long COVID, primary outcomes reported are neurologic, cardiac and respiratory in nature. However, several studies have also reported an increase in gastrointestinal (GI) symptoms and syndromes following COVID-19. This study of PASC will include extensive analyses of GI symptoms, determine if people with pre-existing irritable bowel syndrome (IBS) are at higher risk of developing PASC generally or PASC-GI, and which biomarkers are impacted and to what degree.
Concordance between self-reported SARS-CoV-2 positivity and laboratory-confirmed positivity
This paper examined how closely CoVHORT participants’ reported illness dates matched their laboratory-confirmed COVID-19 test dates. Working with the Arizona Department of Health Services, and using secure data-sharing agreements, we compared responses from a subset of participants.
Understanding Low COVID-19 Booster Uptake among US Adults
Vaccinations against SARS-CoV-2 have consistently been shown to reduce the risk of severe COVID-19 disease. However, uptake of boosters has stalled in the United States at less than 20% of the eligible population. The objective of this study was to assess the reasons for not having obtained a bivalent booster within an existing COVID-19 cohort.
Pre-existing conditions associated with post-acute sequelae of COVID-19
Post-acute sequelae of COVID-19 (PASC) are conditions that occur or remain at least 28 days after SARS-CoV-2 infection. While some risk factors for PASC have been identified, little is known about pre-existing conditions that render one susceptible to developing PASC.
Difference in Perceptions of Individual and Government-Level COVID-19 Prevention Measures Based on Vaccine Willingness
Given the patchwork of federal and state COVID-19 responses and the politicization of vaccination in the United States, investigating whether individuals support governmental or individual mitigation approaches can influence and inform future legal and policy approaches to infectious diseases
Persisting gastrointestinal symptoms and post-infectious irritable bowel syndrome following SARS-CoV-2 infection: results from the Arizona CoVHORT
The latest research from the Arizona CoVHORT followed persons with a confirmed SARS-CoV-2 infection from May 2020 through October 2021 in order to determine how acute gastrointestinal symptoms (GI) persist following COVID-19. It’s important to understand if there’s an association between SARS-CoV-2 infection and persistent GI symptoms because these symptoms can have considerable impacts to a person’s quality of life and result in a diagnosis of long-term GI disorders like Irritable Bowel Syndrome (IBS).
Consequences of COVID-19 on Adolescents in Arizona: A Longitudinal Study Protocol
The long-term impact of COVID-19 is unknown. We developed a 5-year prospective cohort study designed to generate actionable community-informed research about the consequences of COVID-19 on adolescents ages 12–17 years in Arizona.
SARS-CoV-2 infection and subsequent changes in the menstrual cycle among participants in the Arizona CoVHORT Study
We observed 16% of the participants in our sample reported changes to their menstrual cycle after having a COVID-19 infection. The most commonly reported changes were: irregular menstruation (60%), increase in premenstrual syndrome symptoms (PMS) (45%), and infrequent menstruation (35%).
Elucidating symptoms of COVID-19 illness in the Arizona CoVHORT: a longitudinal cohort study
The most commonly reported symptoms of acute COVID-19 in the Arizona CoVHORT were fatigue (82.2%), headache (74.6%), aches, pains or sore muscles (66.3%), loss of taste or smell (62.8) and cough (61.9%).
A Rasch analysis assessing the reliability and validity of the Arizona CoVHORT COVID-19 vaccine questionnaire
Despite the widespread availability of COVID-19 vaccines in the United States, many that have chosen not to be vaccinated have done so because of vaccine hesitancy. This highlights the need for tools that accurately capture the knowledge, attitudes, and beliefs towards COVID-19 vaccines, and provide steps toward improving vaccine acceptance.
COVID-19 vaccination and changes in the mentrual cycle among vaccinated persons
Objective: To describe the characteristics of people who experience changes to their menstrual cycle after COVID-19 vaccination
Post-acute sequelae of COVID-19 in a non-hospitalized cohort: Results from the Arizona CoVHORT
In this manuscript, we sought to examine the clinical presentation and duration of illness of post-acute sequelae of COVID-19 (PASC), or long-COVID, among participants of the CoVHORT who where not hospitalized for their acute SARS-CoV-2 infection. As of February 24, 2021, there were 303 participants in the CoVHORT who had reported a positive test result and having had COVID-19.
Design of the Arizona CoVHORT: A Population-Based COVID-19 Cohort
This manuscript describes a scalable study design that utilizes a wide range of recruitment sources, leveraging electronic data collection to capture and link longitudinal participant data on the current and emerging issues associated with the COVID-19 pandemic.
COVID-19 Infection, the COVID-19 Pandemic, and Changes in Sleep
The objective of this study was to investigate the differences in sleep patterns among individuals with and without laboratory-confirmed SARS-CoV-2 infection. Laboratory-confirmed SARS-CoV-2 test results and self-reported measures recalling sleep habits prior to and during the pandemic were collected from May 2020 to March 2021 among 1,848 individuals in The Arizona CoVHORT Study.